Prediyabetik Gebelerde 50 gr Glukoz Yükleme Testinin Oksidatif Stres ve İnterlökin-8 Parametreleri Üzerine Etkisinin Değerlendirilmesi

Background: The aim of this study is to evaluate the effect 50 g oral glucose tolerance test (OGTT) on oxidative stress and interleukin-8 (IL-8) parameters in prediabetic pregnant women. Materials Methods: Fasting 1 hour blood samples were collected from 79 women who administered gr OGTT. Patients with a level 140–200 mg/dl considered as group. Thereafter, routine biochemical levels superoxide dismutase (SOD), glutathione peroxidase (GPx), malondialdehyde (MDA) measured serum taken during fasting at hour. Results: GPx SOD group remarkably lower than that control (p<0.05). Whereas IL-8 significantly higher When compared OGTT, decreased (p<0.001) (p<0.001). Conclusions: In conclusion, it was found GPX decreased, while increased women; however, when OGTT these patients, increased. These results we obtained suggest systemic inflammation are already present may be triggered by posing negative risk factors for